Starting with the Vanarama National League and Dagenham & Redbridge host Woking.
The Daggers will be looking to bounce back after their Emirates FA Cup disappointment where they fell to a late 1-0 defeat to Bracknell Town of the Isthmian Southern Premier South.
Southend United lock horns with Solihull Moors with Kevin Maher’s side sitting one point above the relegation zone following their ten-point deduction in September.
In the National League South, Aveley face Truro City at Parkside with the former bowing out of the FA Cup during the week to Barnet.
Braintree Town, also look to return to winning ways after losing in the cup to Chesham United, have Weston-super-Mare visiting at Cressing Road.
Chelmsford City head to Slough Town after losing 3-1 in a replay against Whitby Town on Tuesday.
Hoping to get over their penalty shootout loss to Sheppey United, Billericay Town are in Isthmian Premier Division action as they take on Hastings United at New Lodge.
Concord Rangers, a side struggling near the bottom of the table with only one league win this term, welcome second-placed Chatham Town.
Hashtag United make the trip to Kent to face Margate while Canvey Island are also on the road, they face Wingate & Finchley.
High-flying Hornchurch host Bognor Regis Town and will be looking to maintain their unbeaten start to the season at Bridge Avenue.
There are a few local derbies taking place in the Isthmian North Division.
Brentwood Town, who replaced manager Craig Shipman with Keith Rowland, welcome Heybridge Swifts.
Additionally, Brightlingsea Regent, who have only lost two league games this campaign, have Redbridge coming to town.
There is a battle between 13th and 14th at Wallace Binder Ground as Maldon & Tiptree lock horns with Gorleston.
Bowers & Pitsea and Grays Athletic are away from home, facing Lowestoft Town and Walthamstow respectively.
Elsewhere, Basildon United host Enfield and Witham Town play New Salamis at Spa Road.